In the winter, when roads get bad, how will it put chains on the tires when needed?
It will know when to pull into a truck stop for more fuel, and refuel itself how?
It stops at a weigh station and is overweight, the cops just toss a violation notice on the front seat?
If it commits a traffic violation, it will know to pull over for the cops?
If during a random Highway Patrol stop for safety inspection, it has to be pulled out of service, how do the Cops make it stay where it is, who do they notify, and how do they take it out of service?
These are questions for years from now, when there is no person inside the truck at all.
And, at the current point in time, how does the poor soul in the truck let it know it has to pull over, cause the guy has to pee?