Early Use of Hydroxychloroquine Linked to Lower Hospitalization Rates

[zubenelgenubi]

Effects of Antimalarial Drugs on Neuroinflammation
Potential Use for Treatment of COVID-19-Related Neurologic Complications

Antimalarials have unique properties that distinguish them from other anti-inflammatory drugs. (A) They are very lipophilic, which enhances their ability to cross the blood-brain barrier (BBB). Hence, they have the potential to act not only in the periphery but also in the CNS, and could be a useful addition to our limited armamentarium against the SARS-CoV-2 virus. (B) They are non-selective inhibitors of phospholipase A2 isoforms, including cytosolic phospholipase A2 (cPLA2). The latter is not only activated by cytokines but itself generates arachidonic acid, which is metabolized by cyclooxygenase (COX) to pro-inflammatory eicosanoids. Free radicals are produced in this process, which can lead to oxidative damage to the Central Nervous System.

Too sciency for anti-trumpettes. CNN says it's bad, that's all they can handle.

 

[rickyb]

Too sciency for anti-trumpettes. CNN says it's bad, that's all they can handle.

trump is anti science. what do you think the christian right believe in?

the nazis used to be the useful idiots, then they took over. ditto for hte christian right

 

[rickyb]

Effects of Antimalarial Drugs on Neuroinflammation
Potential Use for Treatment of COVID-19-Related Neurologic Complications

Antimalarials have unique properties that distinguish them from other anti-inflammatory drugs. (A) They are very lipophilic, which enhances their ability to cross the blood-brain barrier (BBB). Hence, they have the potential to act not only in the periphery but also in the CNS, and could be a useful addition to our limited armamentarium against the SARS-CoV-2 virus. (B) They are non-selective inhibitors of phospholipase A2 isoforms, including cytosolic phospholipase A2 (cPLA2). The latter is not only activated by cytokines but itself generates arachidonic acid, which is metabolized by cyclooxygenase (COX) to pro-inflammatory eicosanoids. Free radicals are produced in this process, which can lead to oxidative damage to the Central Nervous System.

who wrote this and why do you trust them?

you can find anything on the net that will say anything. doesnt mean its true.

 

[Non sequitur]

Some

Too sciency for anti-trumpettes. CNN says it's bad, that's all they can handle.

If you got a little bit of time this is a good listen. President Trump the other day was asked by a reporter why he is not listening to The experts. His response to the reporter was to name a few of the infectious diseases experts he consults with. This is an interview with one of those experts.

 

[zubenelgenubi]

Some

If you got a little bit of time this is a good listen. President Trump the other day was asked by a reporter why he is not listening to The experts. His response to the reporter was to name a few of the infectious diseases experts he consults with. This is an interview with one of those experts.

I've been attacked for "thinking I know better than the 'experts'". I tell people that I'm just better at picking which experts to listen to.

So what Dr. Kulldorf is saying is that the lock downs of young people are making the pandemic worse? Where have I heard that before?

 

[zubenelgenubi]

I'm just listening to the part about herd immunity. Dr. Sunetra Gupta out of Oxford explains that the threshold for herd immunity can be between 15 and 25%, but that doesn't mean new cases stop, it simply means that the number of new cases start dropping at that point. The point at which new cases diminish to where they aren't alarming may not occur until around 60%.

 

[Jumpin Jack Flash]

Doctors have proven that hydroxychloroquine does nothing for Covid19. Trump and his followers are dopes. After Hydroxychloroquine, Trump Is Now Seeking To Get Another Unproven Drug Approved By The FDA: Report

 

[zubenelgenubi]

Hey! Right at the end he mentions Dr. Gupta. Interesting that he would pick her as an expert to listen to as well. Who else do I know who has mentioned her? Here's a hint: It was me.

 

[rickyb]

Hey! Right at the end he mentions Dr. Gupta. Interesting that he would pick her as an expert to listen to as well. Who else do I know who has mentioned her? Here's a hint: It was me.

i dunno what you say goes against WHO, sweden healthcare ministry for hte most part, forget the other one, consumer reports, michael greger. CDC got corrupted.

it only makes sense to me if you think alot of things are BS like i do.

although sweden didnt do a national lockdown, and im not sure why their cases dropped so suddenly, they probably socially distanced themselves voluntarily because they can self regulate unlike americans who dont believe in science when it comes to corona virus or global warming.

 

[zubenelgenubi]

i dunno what you say goes against WHO, sweden healthcare ministry for hte most part, forget the other one, consumer reports, michael greger. CDC got corrupted.

it only makes sense to me if you think alot of things are BS like i do.

although sweden didnt do a national lockdown, and im not sure why their cases dropped so suddenly, they probably socially distanced themselves voluntarily because they can self regulate unlike americans who dont believe in science when it comes to corona virus or global warming.

A lot of things people say are B.S. because people feel very comfortable talking about things they don't understand, and social media helps push a lot of bad info out for more people to consume. It's all natural for the human condition, though, and I've explained why elsewhere. You have to learn how to think critically about ideas and information, and weigh logic of arguments and the evidence. Most people just go with "everyone knows", and "experts say". In this case they don't even evaluate the credentials of the experts, they rely on the media to let them know what is real and not.

We believe in science. We just understand it better than sheep wearing people clothes. The original strategy for dealing with the pandemic was two weeks to flatten the curve. That was so as not to overwhelm the healthcare system. If you flatten the curve, which most places failed to do anyway, using lockdowns, which caused more elderly to get exposed and die, the number of infected people won't change. The length of pandemic condition simply stretches out. As Dr. Kulldorf from Harvard explained, a targeted approach protecting the high risk people while allowing low risk people to get exposed and generate herd immunity as quickly as possible, would allow everyone yo get back to normal as quickly as possible, while minimizing deaths. A number of us on here, who can read and understand scientific literature, have all been proponents of that exact strategy since early on. Why are we listening to an immunologist's advice on an epidemic and public health policy when he is an expert in neither field?

 

[rickyb]

A lot of things people say are B.S. because people feel very comfortable talking about things they don't understand, and social media helps push a lot of bad info out for more people to consume. It's all natural for the human condition, though, and I've explained why elsewhere. You have to learn how to think critically about ideas and information, and weigh logic of arguments and the evidence. Most people just go with "everyone knows", and "experts say". In this case they don't even evaluate the credentials of the experts, they rely on the media to let them know what is real and not.

We believe in science. We just understand it better than sheep wearing people clothes. The original strategy for dealing with the pandemic was two weeks to flatten the curve. That was so as not to overwhelm the healthcare system. If you flatten the curve, which most places failed to do anyway, using lockdowns, which caused more elderly to get exposed and die, the number of infected people won't change. The length of pandemic condition simply stretches out. As Dr. Kulldorf from Harvard explained, a targeted approach protecting the high risk people while allowing low risk people to get exposed and generate herd immunity as quickly as possible, would allow everyone yo get back to normal as quickly as possible, while minimizing deaths. A number of us on here, who can read and understand scientific literature, have all been proponents of that exact strategy since early on. Why are we listening to an immunologist's advice on an epidemic and public health policy when he is an expert in neither field?

just so you know theres alot of corrupt teachers at harvard and top schools.

WHO, CDC, sweden healthcare ministry i dont necessarily trust, but the guys i do trust like michael greger referred to them.

im a pretty critical thinker myself but i also like to use my reference system to legitimate new sources of info. getting a variety of perspectives too is good.

 

[zubenelgenubi]

just so you know theres alot of corrupt teachers at harvard and top schools.

WHO, CDC, sweden healthcare ministry i dont necessarily trust, but the guys i do trust like michael greger referred to them.

im a pretty critical thinker myself but i also like to use my reference system to legitimate new sources of info. getting a variety of perspectives too is good.

An idea's validity has nothing to do with the person who presents it. I think Fauci is corrupt, but not everything he says is wrong. Do some reading up on epistemology.

 

[rickyb]

A lot of things people say are B.S. because people feel very comfortable talking about things they don't understand, and social media helps push a lot of bad info out for more people to consume. It's all natural for the human condition, though, and I've explained why elsewhere. You have to learn how to think critically about ideas and information, and weigh logic of arguments and the evidence. Most people just go with "everyone knows", and "experts say". In this case they don't even evaluate the credentials of the experts, they rely on the media to let them know what is real and not.

We believe in science. We just understand it better than sheep wearing people clothes. The original strategy for dealing with the pandemic was two weeks to flatten the curve. That was so as not to overwhelm the healthcare system. If you flatten the curve, which most places failed to do anyway, using lockdowns, which caused more elderly to get exposed and die, the number of infected people won't change. The length of pandemic condition simply stretches out. As Dr. Kulldorf from Harvard explained, a targeted approach protecting the high risk people while allowing low risk people to get exposed and generate herd immunity as quickly as possible, would allow everyone yo get back to normal as quickly as possible, while minimizing deaths. A number of us on here, who can read and understand scientific literature, have all been proponents of that exact strategy since early on. Why are we listening to an immunologist's advice on an epidemic and public health policy when he is an expert in neither field?

Doctors on the Front Lines Are Testing New Therapies to Treat COVID-19 - Consumer Reports

In this look at testing being done for new therapies to treat COVID-19, Consumer Reports explains what to know about experimental treatments. Researchers are racing to figure out which ones might work.

www.consumerreports.org

 

[rickyb]

An idea's validity has nothing to do with the person who presents it. I think Fauci is corrupt, but not everything he says is wrong. Do some reading up on epistemology.

you can do less research if you already trust the source. doesnt mean its right but its more likely to be right. of course your trust in the source may be misplaced.

 

[rickyb]

older article on how you get sick from corona and what to do to protect yourself:

Gloves, Face Shields, Masks: Which Protective Gear You Really Need During the Pandemic - Consumer Reports

In this guide to the most useful personal protective equipment for everyday life, Consumer Reports details the protective gear you really need during the pandemic.

www.consumerreports.org

pretty standard stuff in here including ventilation which @zubenelgenubi mentioned but that also assumes you are not social distancing.

 

[zubenelgenubi]

older article on how you get sick from corona and what to do to protect yourself:

Gloves, Face Shields, Masks: Which Protective Gear You Really Need During the Pandemic - Consumer Reports

In this guide to the most useful personal protective equipment for everyday life, Consumer Reports details the protective gear you really need during the pandemic.

www.consumerreports.org

pretty standard stuff in here including ventilation which @zubenelgenubi mentioned but that also assumes you are not social distancing.

I don't really put a lot of faith in a publication whose purpose it is to give recommendations on consumer products when it comes to medical information. Not really a source I would even think to reference. And ventilation is important for the exact reason social distancing indoors is likely not that effective, and almost completely unnecessary when outdoors. Do some reading up on sick building syndrome.

 

[rickyb]

I don't really put a lot of faith in a publication whose purpose it is to give recommendations on consumer products when it comes to medical information. Not really a source I would even think to reference. And ventilation is important for the exact reason social distancing indoors is likely not that effective, and almost completely unnecessary when outdoors. Do some reading up on sick building syndrome.

consumer reports answers a variety of questions for consumer decisions including health related. you should read it more. whats the make and model of your car btw? i drive a scion ia.

social distancing is effective indoors and outside and good ventilation helps too. how do you think you catch a cold? by being away from everyone?

 

[zubenelgenubi]

consumer reports answers a variety of questions for consumer decisions including health related. you should read it more. whats the make and model of your car btw? i drive a scion ia.

social distancing is effective indoors and outside and good ventilation helps too. how do you think you catch a cold? by being away from everyone?

Outdoors social distancing is mostly unnecessary due to air currents, which can be stagnant, admittedly, and microbes not being able to survive UV very well.

Indoors, without proper ventilation, everyone is breathing the same, recycled air. It's particularly bad in highrises and airplanes. So it doesn't matter how far apart you are if the air is being recycled and not ventilated. UV filtration systems can help in indoor spaces that can't vent to the outdoors.

The main reason air in buildings doesn't get vented properly? Increased energy efficiency standards due to climate change alarmism. An example of how climate change alarmism is more harmful to people than climate change.

 

[zubenelgenubi]

If I need some reviews on a new toaster, I'll read consumer reports, maybe, or just user reviews on the internet. When it comes to health and medical information, I'll go right to primary sources. Consumer reports may do some lab tests on materials, but any other health related stuff they report on is necessarily second hand.

 

[rickyb]

Outdoors social distancing is mostly unnecessary due to air currents, which can be stagnant, admittedly, and microbes not being able to survive UV very well.

Indoors, without proper ventilation, everyone is breathing the same, recycled air. It's particularly bad in highrises and airplanes. So it doesn't matter how far apart you are if the air is being recycled and not ventilated. UV filtration systems can help in indoor spaces that can't vent to the outdoors.

The main reason air in buildings doesn't get vented properly? Increased energy efficiency standards due to climate change alarmism. An example of how climate change alarmism is more harmful to people than climate change.

global warming is way more harmful to people than a pandemic. its up there with atomic war which is also a disaster no thanks to trump.

i havent heard anything about highrises. maybe ill check it. airplanes seem like a bad idea.

consumer reports says dont fly but not that the air is recycled:

" Though it may seem like a plane is a perfect environment for an outbreak calamity, it's probably safer than other enclosed spaces because of the air filtration system, according to Erin Bromage, Ph.D., an associate professor of biology at the University of Massachusetts Dartmouth, who's written extensively on infectious disease. Airplane air is fully exchanged every 3 to 5 minutes, he says. '

How to Fly Safely During the Pandemic - Consumer Reports

Consumer Reports shows you how to fly safely during the pandemic and with travelers still facing a patchwork of changing and inconsistent policies, calls for mandatory rules on masks and empty middle seats.

www.consumerreports.org

again another article:
" Keep your distance. If you do need to travel by plane, it’s worth noting that the risk of the disease being spread through an aircraft’s airflow system is relatively low. That’s because the air is continually filtered through a HEPA filter, which can trap viruses, Freedman says. "

How to Stay Safe From Coronavirus While on Planes, Trains, and Buses - Consumer Reports

Consumer Reports shows you how to stay safe from the coronavirus while on the go, whether that’s going for groceries or heading back to work.

www.consumerreports.org