The driver of one of the routes I load never looks at PALs. The moment he picks up a box, he looks directly at the shipping label. Every time I see him sorting anything, he does this. I driver helped him last peak and he did the same exact thing- each and every time he picked up any box that he needed to look at.
I asked one of my other drivers if he cared about sequence numbers and he said he did not... as long as stuff is loaded together and bulk stops are not scattered around.
If you load your crap accurately enough in sequence, the PAL numbers don't REALLY need to be visible, facing out.
Unfortunately, DPS loves pulling splits off my routes. I make it extremely easy for them. That's probably not a good thing...